28 results
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome
 • Urine Chloride
 • Urine Ca/Cr ratio

Dr. Krithika
syndrome from Bartter ... syndrome • Urine ... #syndrome #Bartter ... #Algorithm #nephrology ... #hypokalemia #diagnosis
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Aldosterone: Liddle's Syndrome ... SAME, Cushing Syndrome ... diuretics, Bartter syndrome ... , Gitelman syndrom ... potassium #low #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Cerebral salt wasting syndrome ... Hypothyroidism, Stress ... , Drugs, Syndrome ... syndrome, Cirrhosis ... Algorithm #Causes #nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Syndrome is a rare ... H+ secretion → Hypokalemia ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Diagnosis Algorithm Syndrome ... • Drugs • Pulmonary ... Cirrhosis • Nephrotic ... syndrome • Reduced ... #Hyponatremia #Nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... syndrome - Mutation ... • Bartter syndrome ... Rhabdomyolysis Treatment ... #nephrology #management
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Diagnosis Algorithm Syndrome ... • Drugs • Pulmonary ... Cirrhosis • Nephrotic ... syndrome • Reduced ... #Hyponatremia #Nephrology
Gitelman Syndrome - Management
Treatment includes
 - Electrolyte replacement - K & Mg, preferably Cl salts
Gitelman Syndrome ... - Management Treatment ... In persistent hypokalemia ... #Syndrome #Management ... #Treatment #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Diuretics, Bartter's syndrome ... , Gitelman's syndrome ... acid, Liddle's syndrome ... • Cushing's syndrome ... algorithm #causes #nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
Aldosterone: Cushing syndrome ... excess, Liddle syndrome ... deficiency, Bartter syndrome ... , Gitelman syndrome ... algorithm #diagnosis #nephrology