46 results
Von Willebrand Disease - Clinical Presentation, Diagnosis and Management

- Dr. Eric Strong @DrEricStrong - Strong Medicine
Willebrand Disease - Clinical ... Diagnosis and Management ... Disease #Diagnosis #Management ... #hematology #treatment
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Treatment of Thrombotic ... PLEX and RTX • Short-term ... Thrombocytopenic #Purpura #management ... #treatment #rheumatology ... #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Diagnosis and Management ... disorders • Shear stress-induced ... Syndrome #Diagnosis #Management ... #treatment #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Treatment
Stop offending agents:
 • List as allergies
Systemic Symptoms (DRESS ... ) Syndrome Treatment ... , IVIG etc • Skin ... #Syndrome #Treatment ... #Management #dermatology
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Hypereosinophilic Syndrome • Clinically ... Diagnosis and Treatment ... Syndrome #HES #Hematology ... eosinophils #diagnosis #management
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
bleeding disorder Clinical ... bruising • Skin ... factor VIII) Treatment ... Disease #Diagnosis #Hematology
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
validated for VTE treatment ... studies suggest net clinical ... Bleeding #Risk #Scores ... Anticoagulation #Factors #Hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
characterized by extensive skin ... Skin involvement ... disease: symptomatic treatment ... #Syndrome #dermatology ... #diagnosis #management
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Associated with skin ... severe disease Treatment ... Hydroxychloroquine *Short ... Summary #diagnosis #rheumatology ... #management
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group

< 5%
Diagnosis, causes and management ... cryoglobulinemia vasculitis Clinical ... manifestations - Skin ... neuropathy Treatment ... Cryoglobulinemia #Vasculitis #Rheumatology