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diagnosis liver hepatitis causes druginduced lfts management transaminitis acute acutekidneyinjury aki alcoholic chemistry drug failure gastroenterology hematology hepatocellular idiosyncratic induced
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
dose dependent injury ... symptoms of liver disease ... Idiosyncratic #differential ... gastroenterology #algorithm ... gastroenterology #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... • Iatrogenic: DILI ... extrahepatic source - Tests ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Diagnosis Algorithm ... Skin involvement, Kidney ... Alcohol-related liver disease ... #Diagnosis #Algorithm ... #hepatology
Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal PRE-RENAL Impaired perfusion: •
Causes of Acute Kidney ... Injury ( AKI ) ... • Inflammatory disease ... Postrenal #Failure #Differential ... #Nephrology
Drug Induced Kidney Injury • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy • Osmotic
Drug Induced Kidney ... • Glomerular Disease ... #KidneyInjury #differential ... #diagnosis #algorithm ... #nephrology #Medications
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
→ liver test abnormalities ... Hemochromatosis, Wilson's disease ... HELLP, Celiac disease ... Diagnosis #hepatology ... #algorithm #Transaminitis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
of cholestatic disease ... Alcoholic liver disease ... Cardiac muscle, Kidneys ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Causes of Tremors - Movement Disorders - Differential Diagnosis Algorithm Action Tremor - Occurs During Voluntary Muscle
Movement Disorders - Differential ... Diagnosis Algorithm ... Tremor - Occurs at Rest ... Thyroid, Liver, Kidney ... #Differential #
Guide to Acute Kidney Injury (AKI) What to ask/look for: - HPI, PMH, full ROS
Guide to Acute Kidney ... Injury (AKI) ... - Pre-renal disease ... #Diagnosis #Algorithm ... #Causes #Differential
Alcoholic Hepatitis - Management Algorithm Assess Eligibility for Treatment: - Maddrey Discriminant Function ≥ (or possibly MELD
Treatment: - Acute kidney ... injury with serum ... - Concomitant diseases ... HCV, DILI, HCC, ... #hepatology
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