10 results
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... Stepwise Diagnosis Algorithm ... Skin involvement, Kidney ... #Liver #Injury ... #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - ... (>1000): • DILI ... injury) • Ischemic ... #Function #Tests ... Differential #Diagnosis #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... extrahepatic source - Tests ... #injury #hepatitis ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Circulation Failure Kidney ... Alcohol-Associated Hepatitis ... Injury (DILI) ... Viral Hepatitis ... Failure #Cirrhosis #Hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Check Acute viral hepatitis ... Check Acute viral hepatitis ... Cardiac muscle, Kidneys ... #chemistry #diagnosis ... #differential #Hepatology
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Liver Function Test ... skeletal muscle, kidney ... abnormality vs bone Bili ... Hepatocellular injury ... Transaminitis #diagnosis #hepatology
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Liver Function Tests ... bilirubin (Conjugated/DBili ... hepatocellular injury ... #Function #Tests ... Interpretation #diagnosis #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injuryliver ... test abnormalities ... #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Autoimmune Hepatitis - Testing Algorithm
Individual Tests:
 • F-Actin (Smooth Muscle) Antibody, IgG by ELISA with Reflex
Autoimmune Hepatitis ... Individual Tests ... IgG by IFA • Liver ... /Kidney Microsome ... #hepatology
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... Treatment: - Acute kidney ... injury with serum ... HCV, DILI, HCC, ... #hepatology