20 results
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
other autoimmune diseases ... lupus erythematosus ... (SLE) Signs / ... Pathophysiology #Diagnosis #Signs ... #Symptoms
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
effusion, Restrictive lung ... Demyelinating syndromes ... pain (20%) Renal disease ... #erythematosus ... #signs #symptoms
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
autoimmune disease ... elbows/wrists and knees ... skin thickening Signs ... (interstitial lung ... rheumatology #diagnosis #signs
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
involvement: Intractable nausea ... autoimmune disorders (Systemic ... lupus erythematosus ... diagnosis #neurology #symptoms ... #signs
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Myositis 4% - Lung ... #Lupus #Erythematosus ... autoantibodies #signs ... #symptoms #mimickers
Rhombencephalitis
BACTERIAL
- Listeria (biphasic illness with bulbar dysfunction occurring later)
- Mycobacterium tuberculosis
- Pneumococcus
- Brucella
- Borrelia (Lyme Disease)
-
- Systemic Lupus ... Erythematosus ... (bulbar symptoms ... - small cell lung ... Differential #Diagnosis #Causes
Causes of Peripheral and Central Vertigo
PERIPHERAL VERTIGO
1. Benign paroxysmal positional vertigo (BPPV) - Short-lived (typically less
Causes of Peripheral ... Long symptom-free ... (Wallenberg's syndrome ... Syndrome usually ... varying neurologic signs
Rare Causes of Abdominal Pain
 • Hereditary Angioneurotic Edema - Recurrent visceral that may by swelling
- May involve symptoms ... cardiovascular system ... neuropsychiatric symptoms ... patient is in the knee-to-chest ... Positive Carnett's sign
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... ischemia - Skin: erythematous ... lupus erythematosus ... Symptoms (Sx) in ... purpura: strong sign
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
granulomas within the lungs ... the lymphatic system ... are not caused ... 5-10%, nervous system ... Diagnosis #Management #Signs