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diagnosis differential hyperkalemia potassium high algorithm aniongap diabetic disorders diuresis diuretics eudka euglycemic excretion gout hyperuricemia hypokalemia k ketoacidosis ketones
Causes of HyperKalemia - Differential Diagnosis Increased extracellular K+: • Tissue injury • Hemolysis • Rhabdomyolysis •
Causes of HyperKalemia ... • Metabolic acidosis ... Succinylcholine • Diabetes ... • Calcineurin inhibitor ... blockers - MCW Nephrology
Euglycemic Diabetic Ketoacidosis (EuDKA) SGLT2 Inhibitors Increasing Indications Significant Adverse Drug Effects Definition of EuDKA • Metabolic acidosis with pH
Euglycemic Diabetic ... (EuDKA) SGLT2 Inhibitors ... EuDKA • Metabolic acidosis ... EuDKA #diagnosis #management ... #endocrinology
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis Causes of High-anion Gap Acidosis: • Lactic acidosis
Causes of High-anion ... Causes of High-anion ... Ketoacidosis: Diabetic ... Calcineurin inhibitors ... #nephrology
Hyperuricemia - Differential Diagnosis Algorithm Primary - Over-production • Increased turnover of nucleotides Primary
Hyperparathyroidism • Diabetic ... acidosis - Renal ... drugs • ACE inhibitors ... Diagnosis #Algorithm #endocrinology ... #causes
Ketosis Disorders Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
• Diabetic ketoacidosis ... (DKA) - caused ... seen with SGLT inhibitors ... differential #diagnosis #management ... #endocrinology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
irrigation • Management ... • Nephrogenic diabetes ... Kidney stones caused ... DDAVP) • Central diabetes ... Excretion #Diuresis #Nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
NSAIDs • ACE Inhibitors ... (Uncontrolled diabetes ... - Metabolic acidosis ... differential #diagnosis #causes ... potassium #high #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
NSAIDs • ACE Inhibitors ... (Uncontrolled diabetes ... - Metabolic acidosis ... differential #diagnosis #causes ... potassium #high #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Diagnosis and Management ... Weakness, cramping, nausea ... infusion, Calcineurin inhibitors ... only if no clear cause ... Treatment #potassium #nephrology
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... (treatment of diabetic ... carbonic anhydrase inhibitors ... Renal tubular acidosis ... differential #diagnosis #nephrology
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