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hepatology diagnosis differential transaminitis causes management dili gastroenterology hepatitis indications treatment abnormal aclf acutekidneyinjury aki albumin ascites chemistry chronic drug
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - ... • NAFLD • Cirrhosis ... Hepatopathy • Acute ... injury) • Ischemic ... Function #Tests #LFTs
Focused evaluation algorithm for acute liver injury #Liver #Injury #Acute #Evaluation #Algorithm #Diagnosis #Hepatology
Focused evaluation algorithm ... for acute liver ... injury #Liver ... #Injury #Acute ... #Evaluation #Algorithm
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... Injury Transaminase ... > 20x normal - Acute ... CMV), Alcoholic cirrhosis ... #LFTs #transaminitis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... Mixed - Check Acute ... injury < 26 weeks ... hepatitis: < 1 • Cirrhosis ... transaminitis #LFTs
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... those with CLD (± cirrhosis ... Injury (DILI) ... EmoryGastroHep #ACLF #Acute ... #Failure #Cirrhosis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... Liver Injury: ... Liver Injury: ... hepatitis: < 1 • Cirrhosis
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... Injury → liver ... Injury Differential ... Diagnosis #hepatology #algorithm ... Transaminitis #LFTs
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Injury (DILI) ... dose dependent injury ... Chronic - ongoing ↑ LFTs ... or symptoms of liver ... gastroenterology #algorithm
Indications for Albumin for Management of Cirrhosis • Large volume paracentesis (>5 liter) - 8g per
Management of Cirrhosis ... ) - 8g per liter ... ascites removed • Acute ... kidney injury ( ... Indications #Management #Cirrhosis
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... Infiltrative • Cirrhosis ... • Others #LFTs ... Differential #Diagnosis #Algorithm
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