13 results
diagnosis hepatology differential transaminitis treatment blood cirrhosis gastroenterology hematology indications product reactions aclf aih aki albumin algorithm autoimmune chemistry chronic
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... Tests (LFTs) - ... Hepatopathy • Acute ... injury) • Ischemic ... Function #Tests #LFTs
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... Mixed - Check Acute ... injury < 26 weeks ... muscle injury: ... transaminitis #LFTs
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Injury (DILI) ... dose dependent injury ... Chronic - ongoing ↑ LFTs ... differential #Diagnosis #Management
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... Injury Transaminase ... > 20x normal - Acute ... #Patterns #Liver ... #LFTs #transaminitis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Injury (DILI) ... Hepatitis Procedures Management ... EmoryGastroHep #ACLF #Acute ... gastroenterology #management
Indications for Albumin for Management of Cirrhosis • Large volume paracentesis (>5 liter) - 8g per
for Albumin for Management ... ) - 8g per liter ... ascites removed • Acute ... kidney injury ( ... #Indications #Management
Metformin Associated Lactic Acidosis (MALA) Pathophysiology of MALA - Metformin interferes with the activity of the
cycle found in the liver ... gastrointestinal distress and acute ... kidney injury are ... Toxicology #Diagnosis #Management
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
immunosuppression • Acute ... injury (INR > 2 ... > 3 mg/dL) or acute ... liver failure ... #Indications #management
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
subclinical disease to acute ... liver failure ... hepatocellular pattern of liver ... injury, though ... AIH #Diagnosis #Management
Acute Kidney Injury (AKI) - Management Principles Prerenal - Correct hemodynamic derangements: • If low preload →
Acute Kidney Injury ... (AKI) - Management ... Treat underlying liver ... #Kidney #Injury ... #treatment #management
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