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Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... and Management ... • Immunologic Workup ... Erythematosus #Diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... • Immunologic Workup ... Usual therapeutic management ... #rheumatology #diagnosis ... #management
Pulmonary Renal Syndrome: Investigations and Management #Pulmonary #Renal #Syndrome #Diagnosis #Workup #Management
Pulmonary Renal Syndrome ... Investigations and Management ... Pulmonary #Renal #Syndrome ... #Diagnosis #Workup ... #Management
Hyperthyroidism (low TSH, High T4/T3) - Diagnostic Algorithm Radioactive iodine scan – get if concern for nodular
High T4/T3) - Diagnostic ... specific, so if positive ... workup choices ... AND management options ... #Algorithm #Workup
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... healthy adults, and should ... SLE), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... #rheumatology #diagnosis
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal Syndrome ... Differential Diagnosis ... : - ANCA-positive ... Complex: Systemic lupus ... #differential #diagnosis
Hypoglycemia Workup and Differential Diagnosis Workup: • Sulfonylurea Labs • Anti-lnsulin Ab - Insulin Autoimmune Syndrome •
Hypoglycemia Workup ... Workup: • Sulfonylurea ... Insulin Autoimmune Syndrome ... stores in liver should ... Insulin Autoimmune Syndrome
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... Demyelinating syndromes ... haemolytic Coombs positive ... Thrombocytopenia #Lupus ... signs #symptoms #diagnosis
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... block • Sjogren syndrome ... #Systemic #Lupus ... #SLE #Summary #diagnosis ... #rheumatology #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Demyelinating Syndrome ... permeability Diagnosis ... rheumatology #cerebritis #diagnosis ... #management #treatment
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