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lupus neurology sle anemia antibody apml calcium cerebritis chronic classification cll cns cppd deposition differentiation disease diseases druginduced erythematosus gravis
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
• Blood smear: Differential ... 2) LOOK FOR a cause ... → Systematic screening ... #management #treatment ... #rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Immunosuppression • Autoimmune ... Lymphoma Workup ... Lymphoma Treatment ... classification #hematology ... #oncology #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... CNS #neurology #rheumatology ... #management #treatment
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... identical to the non-Hodgkin ... microglobulin Treatment ... #workup #oncology ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Hemopathies+++: Hodgkin ... solid cancers • Autoimmune ... #management #treatment ... #summary #rheumatology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
effects of SCC or Hodgkin ... lymphoma - Autoimmune ... life-threatening Differential ... Drugs, infection, surgery ... #management #neurology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Nephrogenic DI Hematologic ... Malignancy Risk: • Non-Hodgkins ... Adenocarcinoma Treatment ... #Rheumatology # ... Diagnosis #Management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Pathophysiology ... initiation • Differential ... #management #hematology ... #oncology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... months to years) Systemic ... druginduced #lupus #sle #comparison ... #table #rheumatology ... #diagnosis #management
Subglottic stenoses (SGS) during systemic diseases Subglottic stenosis (SGS) = congenital (children) or acquired (adult) characterized by
Work-up: • Biology ... Laryngotracheal surgery ... #diseases #differential ... #diagnosis #causes ... #rheumatology
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