22 results
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... ), RA, crystal disease ... Inflammatory, crystalline disease ... #rheumatology # ... #differential #diagnosis
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... Antiphospholipid-antibody ... #joint #pain #skin ... #differential #diagnosis ... #rheumatology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
syndrome Anti-Scl ... polyangiitis U1-RNP antibody ... Endomyseal antibody ... #diagnosis #table ... #rheumatology #
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pulmonary ... Spondyloarthropathies, SLE • Pulmonary ... Antiphospholipid-antibody ... #differential #diagnosis ... #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear Antibody ... scleroderma) - Anti-Scl ... Antineutrophil #antibodies #diagnosis ... #rheumatology # ... diseases
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Arthritis Differential Diagnosis ... - Autoimmune Rheumatologic ... gonorrhea) • Bacterial ... #Differential #Diagnosis ... #MSK #rheumatology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Disease: • Pain ... disease must be ... infections related to bacterial ... #Pain #MSK #rheumatology ... #differential #diagnosis
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
), PAH (pulmonary ... arterial HTN) ... Musculoskeletal: joint ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
- Differential Diagnosis ... athletic training, Pulmonary ... Structural: Celiac disease ... Bypass surgery, Bacterial ... Algorithm #ferritin #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... of the affected joint ... (to support a diagnosis ... laboratory #workup #diagnosis ... #testing #Rheumatology