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diagnosis ana antinuclear vasculitis antibodies classification neurology signs table autoantibodies joint patterns activation algorithm antineutrophil aortitis arthritis arthropathies arthropathy associations
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
BEE Syndromes - ... and less common diseases ... Vogt-Koyanagi-Harada (VKH) disease ... • Systemic lupus ... disease • Multiple
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Associated Rheumatic Diseases ... lupus erythematosus ... tissue disease ... Syndrome (SS), ... #patterns #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
lupus erythematosus ... cases • Sjögren syndrome ... connective tissue disease ... antibodies #diagnosis #rheumatology ... #diseases
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
lupus erythematosus ... Syndrome (SS), ... : Lupus (SLE), Systemic ... Arthritis, Sjögren Syndrome ... #patterns #rheumatology
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Churg-Strauss syndrome ... lupus erythematosus ... - Schnitzler syndrome ... - Sjögren syndrome ... Vessels #Diagnosis #Rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... block • Sjogren syndrome ... polymyositis overlap syndrome ... #Lupus #Erythematosus ... diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ACLE) • Erythematous ... lymphoma • Evans' syndrome ... Shrinking lung syndrome ... #Diagnosis #Rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
arteritis, Cogan's Syndrome ... Disease, Polyarteritis ... : IgG4-Related Disease ... lupus erythematosus ... #Diagnosis #rheumatology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Congenital Diseases ... Wiskott-Aldrich syndrome ... and Autoimmune Diseases ... : • Systemic lupus ... #Diagnosis #Hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... auto-immune, Infectious diseases ... sclerosis, Still's disease ... #Systemic #Lupus ... #rheumatology
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