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diagnosis management clinical pharmacology differential algorithm pathophysiology cardiology treatment pocus nephrology physicalexam causes video table comparison medications radiology msk echocardiogram
Antibiotic Classification by Mechanism of Action Cell Wall Synthesis: Penicillins Cephalosporins Carbapenems Monobactams Beta-lactamase inhibitors Glycopeptides Protein
by Mechanism of Action ... Cell Wall Synthesis ... Folic Acid Synthesis ... Metronidazole mRNA Synthesis ... Pharmacology #Mechanism #Action
Antibiotics - Mechanisms and Sites of Action Inhibit Cell Wall Synthesis or Function - Beta Lactams,
Mechanisms and Sites of Action ... Inhibit Cell Wall Synthesis ... Inhibit Protein Synthesis ... Inhibit Protein Synthesis ... Mechanisms #Sites #Action
Classification of Some Antimicrobial Agents by Their Sites of Action Inhibitors of metabolism: Sulfonamides, Trimethoprim Inhibitors of cell
Their Sites of Action ... Inhibitors of cell wall synthesis ... Inhibitors of protein synthesis ... acid function or synthesis ... mechanism #sites #action
Renal Effect of NSAIDs Inhibition of Prostaglandin Synthesis - Renal disease, Cardiovascular disease -> Decreased renal
Prostaglandin Synthesis ... prostaglandin synthesis ... , leaving actions
Insulin and Glucagon Pathophysiology Insulin: • Glucose utilization (Glycolysis) • Glucose storage (Glycogenesis) • Fat synthesis
Glycogenesis) • Fat synthesis ... Lipogenesis) • Protein synthesis ... tissues Glucagon Actions ... : • Glucose synthesis
Mechanism of Action of Bile Acid Sequestrants Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Mechanism of Action ... Hepatic Bile Acid Synthesis
Pharmaceutical Management of Hyperthyroidism / Thyroid Storm Beta-Blockers • Decreases sympathetic hyperactivity • Partially blocks peripheral conversion
PTU) • Blocks synthesis ... Faster onset of action ... Methimazole • Blocks synthesis
Vitamin D Metabolism Fat-soluble vitamin Sources: dermal synthesis and food (dairy products, fish) Active form: calcitriol (1,25-OH Vitamin D) Main
Sources: dermal synthesis ... products, fish) Active
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
Vit-D (1-25-OH2) synthesis ... and action -> Decr
Fever - Pyrogen Pathophysiology EXOGENOUS PYROGEN • Bacteria: Lipopolysaccharide components, peptidoglycans and muramyl peptide derivatives, Toxins •
macrophages) → Synthesis ... vasculature via: • Active ... Pyrogen → Induce synthesis
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