1023 results
Antibiotic Classification by Mechanism of Action

Cell Wall Synthesis: 
Penicillins 
Cephalosporins 
Carbapenems 
Monobactams 
Beta-lactamase inhibitors
Glycopeptides 

 Protein
Action Cell Wall Synthesis ... Folic Acid Synthesis ... Metronidazole mRNA Synthesis ... Classification #Pharmacology ... Text: Clinical Pharmacology
Arachidonic acid pathway and drugs which affect it.

#Pharmacology #Pathophysiology #ArachidonicAcid #Pathways #COX #Prostaglandins #Prostacyclins #Leukotrienes #Synthesis

**
#Pharmacology #Pathophysiology ... #Leukotrienes #Synthesis ... Text: Clinical Pharmacology
Antibiotics - Mechanisms and Sites of Action 

Inhibit Cell Wall Synthesis or Function 
- Beta Lactams,
Inhibit Cell Wall Synthesis ... Inhibit Protein Synthesis ... Inhibit Protein Synthesis ... Inhibits Folate Synthesis ... Sites #Action #Pharmacology
Classification of Some Antimicrobial Agents by Their Sites of Action
Inhibitors of metabolism: Sulfonamides, Trimethoprim
Inhibitors of cell
Inhibitors of cell wall synthesis ... Inhibitors of protein synthesis ... acid function or synthesis ... sites #action #pharmacology
Renal Effect of NSAIDs Inhibition of Prostaglandin Synthesis

 - Renal disease, Cardiovascular disease -> Decreased renal
Prostaglandin Synthesis ... prostaglandin synthesis ... Prostaglandins #Pharmacology
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
Inhibition of cytokine synthesis ... Inhibition of cytokine synthesis ... Immunosuppressant #Drugs #Pharmacology
Mechanism of Action of Bile Acid Sequestrants
Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Hepatic Bile Acid Synthesis ... pathophysiology #pharmacology
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Decreased Aldosterone Synthesis ... Pathophysiology #Pharmacology
Pharmaceutical Management of Hyperthyroidism / Thyroid Storm
Beta-Blockers 
• Decreases sympathetic hyperactivity 
• Partially blocks peripheral conversion
PTU) • Blocks synthesis ... Methimazole • Blocks synthesis ... ThyroidStorm #Management #Pharmacology
Antidepressant Medications Decision Aid
 - The choice of depression medications in primary care is difficult as
efficacy (recent AHRQ Synthesis ... SNRIs #Selection #Pharmacology