17 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Photosensitivity, Alopecia ... • Immunologic Workup ... #Systemic #Erythematosus ... #Diagnosis #Management
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
) Differential Diagnosis ... erythematosus ... • Loose anagen syndrome ... #dermatology #Differential ... #causes
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Diagnosis Framework ... : Lupus erythematosus ... , Loose anagen syndrome ... Vitamin D levels Systemic ... #dermatology #Hairloss
Mucous Membrane Disorder - Differential Diagnosis Algorithm
Erosions/Ulcers/Blisters
 - Primary Dermatologic Diseases
     •
- Differential Diagnosis ... necrolysis - Systemic ... lupus erythematosus ... MucousMembranes #dermatology ... #Algorithm #causes
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Lupus Erythematosus ... Demyelinating Syndrome ... autoantibodies that will cause ... #Lupus #Erythematosus ... #management #treatment
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
• Bullous systemic ... lupus erythematous ... Vesiculobullous #SkinRash ... #dermatology #Differential ... #causes
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... severe disease Treatment ... #Lupus #Erythematosus ... #SLE #Summary #diagnosis ... management
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... antiphospholipid syndrome ... Lupus Erythematosus ... CHAMPS #Mnemonic #diagnosis ... #differential #hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
months to years) Systemic ... Lupus Erythematosus ... Photosensitivity, Alopecia ... sle #comparison #table ... diagnosis #management
Diffuse Hair Loss (Alopecia) - Differential Diagnosis Algorithm

Scarring - Irreversible-biopsy required
 • Lupus erythematosus
 • Lichen
Irreversible-biopsy required • Lupus ... erythematosus ... • Loose anagen syndrome ... #dermatology #Differential ... #causes