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diagnosis differential endocrinology dermatology generalized pruritus secondary systemic anemia breast discharge dyslipidemia hematology hyperlipidemia hypothyroid interpretation lipidprofiles management normocytic pediatrics
Laboratory Evaluation of Patients for Thyroid Disease Hyperthyroidism: • Graves disease - TSH low; free T4
Disease Hyperthyroidism ... high; in some cases ... iodine uptake Hypothyroidism ... disease course #hypothyroid ... #hyperthyroid #
Approach to Thyroid Function Tests in the Evaluation of Hyperthyroidism • Low TSH, Low normal T4
Approach to Thyroid ... T4 → Possibly Central ... +/- T3 → Primary ... symmetrically enlarged thyroid ... #algorithm #diagnosis
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential Diagnosis Algorithm ... Causes == Primary ... Creatinine & BUN: • Chronic ... /uremia TSH & T4 ... #causes
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
• Insomnia Primary ... goiter • Toxic diffuse ... T3 • ↑ Free T4 ... Glucocorticoids: Reduce T4 ... #causes #diagnosis
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Reticulocytosis • Primary ... RA, SLE, PRV, Chronic ... Anemias (MAHA) - Abnormal ... Cancer • Hypothyroid
Abnormal Lipid Profiles - Differential Diagnosis Algorithm Increased Cholesterol and Triglycerides - Genetic Causes
Abnormal Lipid Profiles ... Differential Diagnosis Algorithm ... Diabetes • Hypothyroidism ... Deficiency • Primary ... • Hypothyroid
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary ... Creatinine & BUN: • Chronic ... /uremia TSH & T4 ... : • Hypothyroidism ... #causes
Breast Discharge - Differential Diagnosis Algorithm High Prolactin + Normal TSH • Microprolactinoma • Steroid Hormone Intake
Differential Diagnosis Algorithm ... Hormone Intake • Chronic ... + High TSH • Primary ... Hypothyroidism ... Endocrinology #Causes
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
Differential Diagnosis Algorithm ... Deprivation • Primary ... Dwarfism) • Hypothyroidism ... Chronic UTI) • ... endocrinology #causes
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary WHAT? • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
disease of unknown cause ... degenerative diseases, hypothyroidism ... DIAGNOSIS: • PMR primarily ... creatine kinase, and thyroid-stimulating ... treatment for PMR is a chronic
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