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nephrology diagnosis nejm renal acute akd aki algorithm biomarkers causes chronic clock complications differential ebm gfr gout hyperuricemia kidneydisease kidneyinjury
Definitions of AKI, CKD, AKD Acute Kidney Injury (AKI): • Increase in SCr by 2 50% within
• GFR < 60 ml/min ... • AKI, OR • GFR ... • Decrease in GFR ... • GFR ≥ 60 ml/min ... #AKD #Definitions
The GFR Clock for Staging CKD Staging CKD is most frequently done by calculating the estimated glomerular
The GFR Clock for ... as a proxy for kidney ... Using the GFR clock ... #Diagnosis #Nephro ... #CKD #EGFR #Staging
Interpreting Kidney Biomarkers ↑ Creatinine: • AKI, CKD • Medications that lead to nephroprotective ↓ in
Interpreting Kidney ... Creatinine: • AKI, CKD ... nephroprotective ↓ in GFR ... Cystatin C: • AKI, CKD ... hyperthyroidism ↓ eGFR
Effects of Prostaglandins and NSAIDs on the Kidney Effects of Prostaglandins on the Kidney: • The vasodilatory
perfusion of remaining nephrons ... maintaining baseline GFR ... setting of modest GFR ... with GFR > 30 and ... avoidance with GFR
Effects of a Low-Protein, Low-Salt Diet on the Afferent Arteriole. A lower intake of dietary protein
#Pathophys #Nephro ... #CKD #LowProteinDiet ... #GFR #NEJM
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
Causes of Chronic Kidney ... Algorithm Decreased kidney ... function (eGFR ... ) • Multiple myeloma ... Hyperphosphatemia #CKD
Chronic Kidney Disease (CKD): Individualize BP-lowering therapy and treatment targets in people with frailty, high risk of
Chronic Kidney Disease ... (CKD): Individualize ... Initial dips in eGFR ... GFR reductions of ... #CKD #eGFR #Kidney
Effect of Tolvaptan on the Estimated Glomerular Filtration Rate (GFR). #EBM #Nephro #Pharm #Tolvaptam #PCKD #PolyCysticKidneyDisease
Filtration Rate (GFR ... #EBM #Nephro #Pharm ... #Tolvaptam #PCKD
Hyperuricemia: Pathogenesis and Complications - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
arteriole in the nephron ... filtration rate (GFR ... decr ability of kidneys ... tubule in the nephron ... blood into the nephron
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