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diagnosis nephrology differential pharmacology acute aki algorithm causes dosing table workup akd biomarkers calculation chronic clearance clock cockcroftgault complications creatinine
Definitions of AKI, CKD, AKD Acute Kidney Injury (AKI): • Increase in SCr by 2 50% within
• GFR < 60 ml/min ... • AKI, OR • GFR ... • Decrease in GFR ... • GFR ≥ 60 ml/min ... #AKD #Definitions
Interpreting Kidney Biomarkers ↑ Creatinine: • AKI, CKD • Medications that lead to nephroprotective ↓ in
Interpreting Kidney ... Creatinine: • AKI, CKD ... nephroprotective ↓ in GFR ... hyperthyroidism ↓ eGFR ... #renal #diagnosis
The GFR Clock for Staging CKD Staging CKD is most frequently done by calculating the estimated glomerular
The GFR Clock for ... as a proxy for kidney ... filtered in the kidney ... Using the GFR clock ... #EGFR #Staging
Effects of Prostaglandins and NSAIDs on the Kidney Effects of Prostaglandins on the Kidney: • The vasodilatory
is increased in CKD ... maintaining baseline GFR ... setting of modest GFR ... with GFR > 30 and ... avoidance with GFR
Adjusted Pain Medication Dosing based on GFR #Renal #Dosing #Pain #Pharmacology #Opiates #CKD #Gabapentin #Table
Dosing based on GFR ... #Renal #Dosing ... Pharmacology #Opiates #CKD
Summary of dosing recommendations in renal impairment of commonly used hypoglycaemic agents #Diabetes #Diabetic #Medications #Pharmacology #Dosing
recommendations in renal ... Dosing #Dosing #Renal ... #Impairment #CKD ... #Table #GFR #Hypoglycemics
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
Causes of Chronic Kidney ... function (eGFR ... 3 months Pre-Renal ... ) • Multiple myeloma ... Hyperphosphatemia #CKD
Hepatorenal Syndrome (HRS) - Diagnostic Criteria HRS-AKI (Acute: previously known as HRS Type 1) • ↑ Creatinine
No structural kidney ... haematuria, Normal renal ... months - eGFR ... ascites • HRS-CKD ... - eGFR < 60ml
To improve the usefulness of the serum creatinine concentration as a marker of kidney function, prediction
as a marker of kidney ... accurately predict GFR ... overestimation of GFR ... used to estimate GFR ... CockcroftGault #EGFR
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 Workup for Hyperphosphatemia - Differential Diagnosis Framework Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
acidosis, DKA Kidney ... Disease: • AKI, CKD ... Increased Renal ... Hypoparathyroidism, Acromegaly, FGFR
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