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diagnosis nephrology causes algorithm aki renal workup acute injury management metabolic rheumatology table treatment acidosis akd alkalosis beriberi biomarkers cardiology
Definitions of AKI, CKD, AKD Acute Kidney Injury (AKI): • Increase in SCr by 2 50% within
• Oliguria Chronic ... (CKD): • GFR < ... • AKI, OR • GFR ... • Decrease in GFR ... • GFR ≥ 60 ml/min
The GFR Clock for Staging CKD Staging CKD is most frequently done by calculating the estimated glomerular
The GFR Clock for ... as a proxy for kidney ... filtered in the kidney ... Using the GFR clock ... #EGFR #Staging
Interpreting Kidney Biomarkers ↑ Creatinine: • AKI, CKD • Medications that lead to nephroprotective ↓ in
Interpreting Kidney ... Creatinine: • AKI, CKD ... nephroprotective ↓ in GFR ... Cystatin C: • AKI, CKD ... #Biomarkers #Kidney
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
- Differential Diagnosis ... function (eGFR ... ) • Multiple myeloma ... Hyperphosphatemia #CKD ... #Nephrology #Differential
Effects of Prostaglandins and NSAIDs on the Kidney Effects of Prostaglandins on the Kidney: • The vasodilatory
is increased in CKD ... maintaining baseline GFR ... setting of modest GFR ... with GFR > 30 and ... avoidance with GFR
Patient factors influencing the selection Of glucose-lowering drugs Other than SGLT2i and metformin in T2D and
metformin in T2D and CKD ... . chronic kidney ... —4 inhibitor, eGFR ... , #KDIGO2020 #CKD ... Management in CKD
Chronic Kidney Disease (CKD): Individualize BP-lowering therapy and treatment targets in people with frailty, high risk of
Chronic Kidney Disease ... (CKD): Individualize ... Initial dips in eGFR ... GFR reductions of ... #CKD #eGFR #Kidney
Workup for Hyperphosphatemia - Differential Diagnosis Framework Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
Hyperphosphatemia - Differential ... acidosis, DKA Kidney ... Disease: • AKI, CKD ... Hypoparathyroidism, Acromegaly, FGFR ... Hyperphosphatemia #Differential
Causes of Hyperuricemia Increased production • Solid-organ transplant • Tumor lysis syndrome • Rhabdomyolysis • Lesch Nyhan
Functionally normal kidneys ... Associated with chronic ... kidney disease ... (CKD) stages 2-5 ... UricAcid #diagnosis #differential
Etiologies of Hypernatremia - Differential Diagnosis GI losses / Insensible losses Sodium Overload Transcellular Movement of Water Central Diabetes Insipidus
Hypernatremia - Differential ... sensitivity in kidneys ... cisplatin) - Chronic ... hypercalcemia - Chronic ... amyloidosis, multiple myeloma
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