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diagnosis kidney differential pathophysiology renal aki algorithm biomarkers calculation causes chronic clearance clock cockcroftgault complications creatinine definitions equations filtrationrate formulas
Definitions of AKI, CKD, AKD Acute Kidney Injury (AKI): • Increase in SCr by 2 50% within
, CKD, AKD Acute ... ): • GFR < 60 ... • GFR < 60 ml/min ... ): • GFR ≥ 60 ... #nephrology #acute
The GFR Clock for Staging CKD Staging CKD is most frequently done by calculating the estimated glomerular
The GFR Clock for ... function rate (eGFR ... Using the GFR clock ... #Diagnosis #Nephro ... #CKD #EGFR #Staging
Interpreting Kidney Biomarkers ↑ Creatinine: • AKI, CKD • Medications that lead to nephroprotective ↓ in
, CKD • Medications ... nephroprotective ↓ in GFR ... , CKD • Obesity ... hyperthyroidism ↓ eGFR ... diagnosis #laboratory #nephrology
Complications of CKD - Patients with stages 1-3 ([GFR] >30 mL/min) of CKD are generally asymptomatic;
Complications of CKD ... with stages 1-3 ([GFR ... >30 mL/min) of CKD ... stages 4-5 (GFR ... Pathophysiology #Nephrology
Regulation of GFR Physiologically, GFR is auto-regulated very precisely with changes in the mean arterial pressure (MAP)
Regulation of GFR ... Physiologically, GFR ... tubuloglomerular, and ... Pathophysiology #Nephrology ... #GFR #FiltrationRate
Effects of Prostaglandins and NSAIDs on the Kidney Effects of Prostaglandins on the Kidney: • The vasodilatory
is increased in CKD ... maintaining baseline GFR ... setting of modest GFR ... with GFR > 30 and ... avoidance with GFR
To improve the usefulness of the serum creatinine concentration as a marker of kidney function, prediction
accurately predict GFR ... overestimation of GFR ... as are seen in acute ... used to estimate GFR ... CockcroftGault #EGFR
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 Effects of a Low-Protein, Low-Salt Diet on the Afferent Arteriole. A lower intake of dietary protein
glomerular damage and ... #Pathophys #Nephro ... #CKD #LowProteinDiet ... #GFR #NEJM
Chronic Kidney Disease (CKD): Individualize BP-lowering therapy and treatment targets in people with frailty, high risk of
Kidney Disease (CKD ... Initial dips in eGFR ... GFR reductions of ... for people with acute ... #CKD #eGFR #Kidney
Workup for Hyperphosphatemia - Differential Diagnosis Framework Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
t-PA, heparin Acute ... Kidney Disease: • AKI ... , CKD Increased ... Hypoparathyroidism, Acromegaly, FGFR ... Workup #phosphate #nephrology
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