23 results
The GFR Clock for Staging CKD

Staging CKD is most frequently done by calculating the estimated glomerular
The GFR Clock for ... function rate (eGFR ... Using the GFR clock ... @JustinBerk #Diagnosis ... #Nephro #CKD #EGFR
Definitions of AKI, CKD, AKD
Acute Kidney Injury (AKI):
 • Increase in SCr by 2 50% within
): • GFR < 60 ... • AKI, OR • GFR ... • Decrease in GFR ... ): • GFR ≥ 60 ... #nephrology #acute
Interpreting Kidney Biomarkers

↑ Creatinine: 
 • AKI, CKD
 • Medications that lead to nephroprotective ↓ in
Creatinine: • AKI, CKD ... nephroprotective ↓ in GFR ... hyperthyroidism ↓ eGFR ... Kidney #renal #diagnosis ... #laboratory #nephrology
Complications of CKD
 - Patients with stages 1-3 ([GFR] >30 mL/min) of CKD are generally asymptomatic;
Complications of CKD ... with stages 1-3 ([GFR ... >30 mL/min) of CKD ... stages 4-5 (GFR ... Pathophysiology #Nephrology
Renal Failure Prognosis - The eGFR and proteinuria offers a general prognosis as demonstrated in the
Prognosis - The eGFR ... #CKD #EGFR #Proteinuria ... Prognosis #Heatmap #Diagnosis ... #Nephrology
Regulation of GFR
Physiologically, GFR is auto-regulated very precisely with changes in the mean arterial pressure (MAP)
Regulation of GFR ... Physiologically, GFR ... tubuloglomerular, and the neuro-hormonal ... Pathophysiology #Nephrology ... #GFR #FiltrationRate
Effects of Prostaglandins and NSAIDs on the Kidney
Effects of Prostaglandins on the Kidney:
 • The vasodilatory
maintaining baseline GFR ... setting of modest GFR ... with GFR > 30 and ... avoidance with GFR ... Kidney #renal #nephrology
Effects of a Low-Protein, Low-Salt Diet on the Afferent Arteriole. A lower intake of dietary protein
#Pathophys #Nephro ... #CKD #LowProteinDiet ... #GFR #NEJM
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm
Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
- Differential Diagnosis ... kidney function (eGFR ... ) • Multiple myeloma ... Hyperphosphatemia #CKD ... KidneyDisease #Nephrology
To improve the usefulness of the serum creatinine concentration as a marker of kidney function, prediction
accurately predict GFR ... overestimation of GFR ... used to estimate GFR ... #Diagnosis #Nephrology ... CockcroftGault #EGFR