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diagnosis nephrology differential hyperkalemia potassium high algorithm alkalosis amyloid amyloidosis k kidney kidneydisease management pharmacology prostaglandins treatment
Effects of Prostaglandins and NSAIDs on the Kidney Effects of Prostaglandins on the Kidney: • The vasodilatory
perfusion of remaining nephrons ... maintaining baseline GFR ... setting of modest GFR ... GFR > 30 and complete ... avoidance with GFR
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
Causes of Chronic ... kidney function (eGFR ... eosinophiluria) • Drugs (NSAlDs ... ) • Multiple myeloma ... Hyperphosphatemia #CKD
Causes of Metabolic Alkalosis: Differential Diagnosis ECF volume contracted: urine chloride concentration <20 meq/L • Gastric alkalosis:
Causes of Metabolic ... acute reversal of chronic ... diuretics after renal ... generally indicates a renal ... markedly reduced GFR
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia: • CKD ... diuretics • NSAIDs ... trauma - Ischemic colonic ... infusions) - Metabolic ... differential #diagnosis #causes
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia: • CKD ... diuretics • NSAIDs ... trauma - Ischemic colonic ... infusions) - Metabolic ... differential #diagnosis #causes
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
K+, ACEi/ARBs, NSAIDs ... esp w oliguria / GFR ... Labs: BMP (Assess GFR ... status to improve GFR ... sufficient if intact GFR
Amyloidosis - Summary Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Bronchiectasis, Chronic ... Manifestations: Renal ... • GI bleeding Neuro ... macroglossia Nails ... hypoadrenalism • Nausea
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