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diagnosis differential causes potassium algorithm metabolic aniongap intercellularshift k kidney kidneydisease management nagma nonaniongap nongap normal pharmacology prostaglandins treatment workup
Effects of Prostaglandins and NSAIDs on the Kidney Effects of Prostaglandins on the Kidney: • The vasodilatory
maintaining baseline GFR ... setting of modest GFR ... GFR > 30 and complete ... avoidance with GFR ... #nephrology #pharmacology
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
kidney function (eGFR ... eosinophiluria) • Drugs (NSAlDs ... Hyperoxaluria • Hypercalcemia ... Hyperphosphatemia #CKD ... #Nephrology #Differential
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis Causes of High-anion Gap Acidosis: • Lactic acidosis
Causes of High-anion ... Causes of High-anion ... Renal acidosis ... Generalized distal nephron ... diagnosis #causes #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
phlebotomy High ... : • CKD • Poorly ... diuretics • NSAIDs ... - Metabolic acidosis ... #nephrology
Normal Anion-Gap Acidosis (NAGMA) - Differential Diagnosis Framework and Workup NAGMA - Chem, ABG or VBG - Calculate Anion
(GFR 20-50 ml/min ... normal Type 4: Hyperkalemic ... - Diarrhea - High ... Surgical drains - Chronic ... Diagnosis #Workup #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
phlebotomy High ... : • CKD • Poorly ... diuretics • NSAIDs ... - Metabolic acidosis ... #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
K+, ACEi/ARBs, NSAIDs ... esp w oliguria / GFR ... Labs: BMP (Assess GFR ... status to improve GFR ... sufficient if intact GFR
Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm Reduced flow through distal nephron - TTKG
through distal nephron ... Creatinine • Chronic ... renal failure ... antagonism • NSAlDs ... IntercellularShift #Nephrology
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