9 results
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... Preferentially captures K ... desired serum K ... Side Effects: Edema ... #medications #pharmacology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... : • CKD • Poorly ... transfusion • HTN and edema ... • Digoxin • K ... K supplement 3
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... : • CKD • Poorly ... transfusion • HTN and edema ... • Digoxin • K ... K supplement 3
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... VBG (acidosis), CK ... - Diuresis (hypervolemia ... caution in HTN & edema ... #Hyperkalemia
Effects of Prostaglandins and NSAIDs on the Kidney
Effects of Prostaglandins on the Kidney:
 • The vasodilatory
retention of Na, K ... is increased in CKD ... prolonged NSAID use in CKD ... with GFR > 30 and ... renal #nephrology #pharmacology
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
: Treatment of Hyperkalemia ... needed, based on K ... who have chronic hyperkalemia ... patients with CKD ... #Pharmacology
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
trial • Minimal K ... Is Dangerous in Hyperkalemia ... • Increases Edema ... volume - increased edema ... NS #comparison #pharmacology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Inhibitors of Na+K+ ... Hyponatremia • Hypercalcemia ... Epithelial Channels (K+ ... Aldosterone Antagonists, K+ ... Diuresis #Nephrology #Pharmacology
Facial Swelling - Differential Diagnosis Framework for Facial Edema

Infectious:
	• Dental abscess
	• Ludwig's angina
	• Vincent's angina
	• Cellulitis
	•
Framework for Facial Edema ... Contact dermatitis (CD ... • Solid facial edema ... carcinoma • Multiple myeloma ... Differential #Diagnosis #PhysicalExam