13 results
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... of eosinophilia ... are asthma, allergy ... #Differential #diagnosis ... #hematology #eosinophilia
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... DRESS - AIN - Eosinophilic ... Syndrome - Chronic Eosinophilic ... coyefish379 #Eosinophilia ... #Causes #hematology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
attributable to eosinophilia ... with blood eosinophilia ... Secondary Causes ... : - Allergic disorders ... #diagnosis #hematology
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Erythroderma - Diagnostic ... Pathophysiology: ... Causes: 1) Exfoliative ... toxin 2) Eosinophils ... #Dermatology #Rash
Causes of Leukocytosis and Leukopenia - Differential Diagnosis
 • Eosinophilia (AEC > 500, hypereosinophilia > 1500):
Causes of Leukocytosis ... - Differential Diagnosis ... • Eosinophilia ... hypereosinophilia > 1500): Allergic ... #causes #hematology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
decades of life Causes ... Disorientation, vertigo Diagnostic ... neutrophils and eosinophils ... Cold #Urticaria #diagnosis ... #rheumatology #
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
- Differential Diagnosis ... ESRD & CAD • Eosinophilic ... Mastocytosis • Other hematologic ... #Differential #Diagnosis ... #hematology #allergy
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
connective tissue disease ... ANCA+ 60% • Eosinophilic ... Antineutrophil #antibodies #diagnosis ... #rheumatology # ... diseases
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... - Differential Diagnosis ... fracture - Patellar dislocation ... Osteosarcoma - Eosinophils ... Knee #Effusions #causes
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... involvement: Anti-GBM Disease ... #differential #diagnosis ... #algorithm #rheumatology