29 results
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
are asthma, allergy ... neoplasms) • Screen also ... glucocorticoid treatment ... #Differential #diagnosis ... #hematology #eosinophilia
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Lysis Syndrome: • Pathophysiology ... #diagnosis #management ... #hematology
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... functional ID) Treatment ... improvement in symptoms ... composite endpoint of all-cause ... #management #cardiology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... pylori test (GI symptoms ... (CVID, WAS), (neurologic ... not required in all ... #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... adult population: also ... mineralization Symptoms ... respiratory failure • Neurologic ... Hyophosphatasia #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
postpartum): • Initial symptoms ... = nonspecific (nausea ... Findings: • ↑AST/ALT ... Liver #Pregnancy #hepatology ... #management #pathophysiology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Most common cause ... Lung Abscess Pathophysiology ... of PCN allergy ... #differential #causes ... #management #treatment
Hepatic Encephalopathy - Diagnosis and Management Summary
Definition:
 • Alteration in brain function manifested by neuropsychiatric symptoms
and Management ... neuropsychiatric symptoms ... of neurologic/cognitive ... #Management #treatment ... #hepatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... (for secondary APS ... Erythematosus #SLE #CNS #neurology ... #management #treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... : >3 symptoms, or ... Renal Failure Treatment ... #management #hematology