39 results
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology of Tumor Lysis ... Tumor Cell Lysis ... -> Uric Acid (low ... Urate Nephropathy (low ... Hypocalcemia • Hyperkalemia
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of Tumor Lysis ... Syndrome (TLS) ... Abnormalities of TLS ... Laboratory TLS ... hydroxide • Hyperkalemia
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis vs Tumor Lysis ... leukapheresis - TLS ... , Elevated Cr, Low ... hydration - Hyperkalemia ... #Syndrome #TLS
Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of
Tumor lysis syndrome ... hyperuricemia, #hyperkalemia ... #Presentation #TLS
Diagnosis of Hypokalemia - Differential Algorithm 

Categorized by Causes: Redistribution, Extrarenal Losses, Renal Losses (High and
Diagnosis of Hypokalemia ... - Differential Algorithm ... Losses (High and Low ... #Diagnosis #Hypokalemia ... #Differential #Algorithm
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
Hyperkalemia: Diagnostic ... algorithm Decreased ... transfusion • Tumor lysis ... • Type 1 #Hyperkalemia ... #Diagnosis #algorithm
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... 6L/day) • For hyperkalemia ... otherwise treat with "hyperkalemia ... wandering_er #Tumor #Lysis ... #Syndrome #TLS
Workup of Hypercalcemia - Differential Diagnosis Algorithm
High or Normal PTH:
 • Hyperparathyroidism: Parathyroid adenoma, Parathyroid hyperplasia,
Workup of Hypercalcemia ... Differential Diagnosis Algorithm ... Low PTH: • High ... PTHrP: - Low ... Differential #Diagnosis #Algorithm
The Diagnostic Approach to Hyperkalemia
Drugs
 - Amiloride
 - Spironolactone
 - Triamterene
 - Trimethoprim
 - Pentamidine
 -
Diagnostic Approach to Hyperkalemia ... deficiency - Heparin/ LMW ... Ketoconazole Low ... Beta-Blockers #Hyperkalemia ... #Algorithm #diagnosis
Hypocalcemia - Differential Diagnosis Algorithm - Low and High PTH
LOW PTH - Hypoparathyroid
 - Congenital (Pediatric)
Differential Diagnosis Algorithm ... - Low and High ... - 25-OH D very low ... Tumor lysis syndrome ... Differential #Diagnosis #Algorithm