923 results
Tumor lysis syndrome (TLS) - Pathophysiology:
→ Massive tumor cell lysis
→ Release of large amounts of K+,
lysis syndrome (TLS ... ) - Pathophysiology ... TumorLysis #syndrome #TLS ... #Pathophysiology
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... Lysis Syndrome (TLS ... TumorLysis #Syndrome #TLS ... #Pathophysiology
Tumor Lysis Syndrome (TLS) Pathophysiology
Culprits: ALL, Burkitt, SCLC
Cells all die at once = ↑Phos, ↓Ca, ↑K,
Lysis Syndrome (TLS ... ) Pathophysiology ... Lysis #Syndrome #TLS ... #Pathophysiology
Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of
acutekidneyinjury #Pathophysiology ... #Presentation #TLS
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... leukapheresis - TLS ... Lysis Syndrome: • Pathophysiology ... Lysis #Syndrome #TLS
H’s and T’s Mnemonic - Causes of Cardiac Arrest
H's - Hypovolemia, Hypoxia, Hydrogen Ions (acidosis), Hyperkalemia
H’s and T’s Mnemonic ... , Hypoglycemia T's ... , Trauma #Hs #Ts
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Lysis Syndrome (TLS ... Abnormalities of TLS ... Laboratory TLS ... mg/dL Clinical TLS ... Treatment of TLS
Diabetes Pathophysiology and Medication Targets

The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... the different pathophysiologic ... #Diabetes #Pathophysiology
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Treatment of Clinical TLS ... MatthewHoMD #TLS
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Lateral Sclerosis (ALS ... ) Summary ALS: combination ... lateral sclerosis Pathophysiology ... (1) limb-onset ALS ... ) bulbar-onset ALS