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diagnosis hematology causes classification atlas deficiency ferritin hodgkins iron lymphoma management morphology rbc testing thrombocytosis thromboticthrombocytopenicpurpura ttp
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
vs Extravascular ... anemia): ... agglutin disease ... #Hemolytic #Intravascular ... #anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... and Intravascular ... Hemolysis - Differential ... - Hemolysis within ... anemia •
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... Diagnosis: • hemolytic ... anemia • Cold ... the RBCs causing intravascular ... #hemolytic #anemia
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... agglutinins disease ... ARUPConsult @ARUPLabs #Hemolytic ... #Anemia #Differential ... #workup #hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency Anemia ... • Iron loss: Intravascular ... (not extravascular ... ) hemolysis, Intensive ... Iron #Deficiency #Anemia
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
spherocytosis, Hemolytic ... Schistocytes - Hemolytic ... , Disseminated intravascular ... Morphology #Atlas #key ... #diagnosis #differential
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
for Hemolytic Anemia ... • AIHA: warm, cold ... IVIG infusion Intravascular ... udaygulati #Hemolytic ... #Anemia #Differential
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
hemorrhage and hemolysis ... result in severe anemia ... reflection of intravascular ... hemolysis Platelet ... anemia Indirect
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Count - Differential ... for workup, including ... blood loss, Acute hemolysis ... , deficiency anemia ... Vasculitides, IBD, Celiac disease
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... nodosum • Immune hemolytic ... anemia • Pain ... Hodgkin Lymphoma Workup ... #oncology #management
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