10 results
Evaluation of Patients with Anemia

Microcytic, Normocytic, Macrocytic, Hemolytic (Intravascular and Extravascular)

#Diagnosis #Anemia #Workup #Macrocytic #Microcytic #Normocytic
Patients with Anemia ... , Macrocytic, Hemolytic ... (Intravascular ... and Extravascular ... #Workup #Macrocytic
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
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Causes of Extravascular ... and Intravascular ... Hemolysis - Differential ... - Hemolysis within ... anemia
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Morphology Atlas • Microcytic ... Lead poisoning • Macrocytic ... spherocytosis, Hemolytic ... Schistocytes - Hemolytic ... , Disseminated intravascular
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
to Anemia - Differential ... Framework by MCV Microcytic ... -100): • Non-hemolytic ... , CKD • Hemolytic ... Infections Macrocytic
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Under 80 = microcytic ... acute blood loss, hemolysis ... for degree of anemia ... #Workup #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... Bleed • Hemolysis ... Microangiopathic Hemolytic ... Anemias (MAHA) ... #Normocytic #Anemia
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
Anemia - Differential ... loss: Intravascular ... (not extravascular ... ) hemolysis, Intensive ... #Deficiency #Anemia
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC) Morphology Microcytic ... (sometimes) Macrocytic ... Microangiopathic Hemolytic ... spherocytosis, Autoimmune hemolytic ... Cold autoimmune hemolytic
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
hemorrhage and hemolysis ... result in severe anemia ... reflection of intravascular ... hemolysis Platelet ... anemia Indirect
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
blood cell count (anemia ... common cytopenia: Macrocytic ... anemia DDX: ... • Aplastic Anemia ... Megaloblastic Anemia