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management table aflp pregnancy disease hellp treatment coagulation differential hepatology obgyn summary syndrome thrombocytopenia transfusion ttphus antimda5 antimda5dm capillary clarksons
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
and Acute Fatty Liver ... child * Severe cases ... #HELLP #AFLP #obstetrics ... #hematology #diagnosis ... #table #comparison
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
Hemolysis, Elevated Liver ... child * Severe cases ... #HELLP #AFLP #Obstetrics ... #OBGyn #Hematology ... #Diagnosis #Comparison
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
) • Advanced Liver ... Septic shock, Obstetric ... Summary #table #comparison ... #diagnosis #hematology
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
weeks • Typical clinical ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis ... #comparison #differential ... #diagnosis #icp
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... ) Differential Diagnosis ... #Pregnancy #hepatology ... #obstetrics #obgyn ... #diagnosis #management
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Non-Hodgkin's Lymphoma - Comparison ... the spleen or liver ... Differential Diagnosis ... #oncology #diagnosis ... #differential #hematology
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
Major Clinical Trials ... NEJM 1999 - ICU FOCUS ... Blood saves lives ... unnecessary and cause ... Transfusion #Thresholds #Hematology
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
decades of life Causes ... and clinical associations ... Cold #Urticaria #diagnosis ... #rheumatology # ... comparison #table
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Drugs, Unknown cause ... Nicolas Taar ... treatment #summary #rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
auricular papules Clinical ... disease and ILD • Liver ... Liver biopsies show ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
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