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Surviving Sepsis 1-Hour Bundle - Initial Resuscitation for Sepsis and Septic Shock 

#SurvivingSepsis #1Hour #OneHour #Bundle
Surviving Sepsis ... Resuscitation for Sepsis ... and Septic Shock ... Resuscitation #CriticalCare ... #Management
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Shock - Differential ... Distributive: Sepsis ... Treatment Goals ... Diagnosis #criticalcare ... #management
Causes, classification and compensatory responses to shock.

Shock can be caused by any pathological process that leads
distributive (septic ... for example, in sepsis ... unresuscitated septic ... #Diagnosis #CriticalCare ... #Shock #Differential
Sepsis - Diagnosis and Management
Life-threatening organ dysfunction caused by a dysregulated host response to infection
SEPTIC SHOCK
and Management ... SHOCK is a subset ... shock are identified ... recognition and treatment ... #QSOFA #SIRS #criticalcare
Shock Types and Classification
DISTRIBUTIVE 66%
 • Sepsis/SIRS, anaphylaxis, adrenal insufficiency, liver failure, toxins, spinal/neurogenic
 • Warm
Shock Types and ... DISTRIBUTIVE 66% • Sepsis ... Cold and Dry #Shock ... Classification #diagnosis #differential ... #criticalcare
Shock - Differential Diagnosis by Classification

Hypovolemic (Intravascular volume depletion)
 - Hemorrhagic 
   • Trauma
Shock - Differential ... Vasodilation) - Septic ... a.k.a. neurogenic shock ... #Differential # ... Classification #Table #CriticalCare
Shock Classification and Differential Diagnosis
SHOCK
 • MAP <65, SBP <90, drop in SBP > 40
 •
Shock Classification ... and Differential ... / Low SVR • Sepsis ... Classification #Differential ... Diagnosis #Types #criticalcare
Systemic Inflammatory Response Syndrome (SIRS)
•	Non-specific (infections vs non-infectious)
•	≥2 of the following:
o	Temp >38°C or <36°C
o	HR >90 bpm
o	RR
>10% bands Sepsis ... Septic Shock • ... >2 mmol/L Management ... recognition & treatment ... #sirs #shock #lactate
American College of Critical Care Medicine algorithm for time-sensitive, goal-directed stepwise management of hemodynamic support in
goal-directed stepwise management ... to next step if shock ... #CriticalCare # ... Peds #Pediatrics #Sepsis ... #Management #StepWise
Vasopressors and Inotropes
 • Norepinephrine - Levophed - "Levo" - Generally thought of as the first
pressor added in shock ... in refractory shock ... Angiotensin - "Ang II" - Sepsis ... Vasopressors #Inotropes #management ... #criticalcare #