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diagnosis management dermatology lupus erythematosus antibody antinuclear granulomatosis polyangiitis signs symptoms syndrome systemic thrombocytopenia workup acr2021 classification comparison disease druginduced
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
in drug-induced SLE ... Vasculitis: • ... Renal-limited vasculitis ... Jcortesizaguirr #ANA ... antibodies #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... mucositis - Rash ... diminished, or tender ... , and SLE) • Urinalysis ... #rheumatology #
Proposed treatment algorithm for antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis #anca #vasculitis #treatment #algorithm #rheumatology #nephrology
Proposed treatment ... cytoplasmic antibody (ANCA ... #anca #vasculitis ... #treatment #algorithm ... #rheumatology #
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Cryoglobulinemia (MIXED) • ANCA ... Associated - SLE ... #Diagnosis #hematology ... #rheumatology #
ANCA-Associated Vasculitis There are many definitions, but most come down to the presence of granulomas (pathologically or
ANCA-Associated ... StanfordChiefs #ANCA ... #Vasculitis #differential ... #diagnosis #algorithm ... #rheumatology
Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021
Polyangiitis (MPA) - ANCA ... Algorithm - ACR ... Polyangiitis #MPA #ANCA ... #Treatment #ACR2021 ... #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Negative IF): • PR3-ANCA ... (C-ANCA): GPA > ... > eGPA • MPO-ANCA ... (P-ANCA): eGPA, ... #rheumatology
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
the Skin - Differential ... Secondary: CTD: SLE ... • ANCA Associated ... #rheumatology # ... differential #diagnosis
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Aortitis - Differential ... Nodosa (PAN), ANCA ... associated vasculitis ... erythematosus (SLE ... #Diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Manifestations: Malar rash ... Workup: - ANA ... Positive in 60-80% of cases ... life-threatening • Treatment ... Management #Summary #rheumatology
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