25 results
Rheumatoid Arthritis Summary
MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
PIP Involvement, Spares ... DIP, Carpal Tunnel ... , Sicca Syndrome ... #rheumatology #signs ... #symptoms
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
peripheries, Carpal ... timel syndrome, ... #Hypothyroid #Features ... #Signs #Symptoms ... #PhysicalExam #Endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
overgrowth: • Carpal ... Tunnel Syndrome ... Acne • Coarse features ... Cardiovascular disease ... #symptoms #endocrinology
Cushing Syndrome - Signs and Symptoms
Generalized: Weight gain, Slow healing of cuts, Increased risk of infections,
Cushing Syndrome ... - Signs and Symptoms ... Increased risk of fractures ... #Signs #Symptoms ... #diagnosis #endocrinology
Kawasaki Disease (Mucocutaneous Lymph Node Syndrome) 
An rare systemic acute febrile vasculitic syndrome. Aetiology unknown. 
Affects
Kawasaki Disease ... febrile vasculitic syndrome ... #Kawasaki #Disease ... #Features #Signs ... #Symptoms #Diagnosis
Characteristic clinical manifestations of Down syndrome 
 
Typical craniofacial appearance 
 • Round face and flat
manifestations of Down syndrome ... • Brushfield spots ... #Downs #Syndrome ... #PhysicalExam #Features ... #Signs #Manifestations
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Short Stature - ... Rickets Dysmorphic Features ... • Cushing's Disease ... Transplant Chronic Disease ... Diagnosis #Algorithm #endocrinology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... /Symptoms: • GH ... deficiency: - Short ... expansion (e.g. carpal ... #FeedbackLoop #endocrinology
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... =>Prader-Willi Syndrome ... Signs/Symptoms ... Incr Skeletal fractures ... • Short stature
Risk Factors and Signs of Copper Deficiency
Risk Factors:
 • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
Risk Factors and Signs ... Chronic diarrhoea, Short ... bowel syndrome, ... , Malnutrition Signs ... #riskfactors #symptoms