10 results
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... (TLS) Tumor Cell ... urine pH) • Hypocalcemia ... #TLS #Pathophysiology
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of Tumor Lysis ... Syndrome (TLS) ... Treatment of TLS ... • Hypocalcemia ... #TumorLysis #Syndrome
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
: • Pathophysiology ... - ACS, AKI, acute ... leukapheresis - TLS ... Syndrome: • Pathophysiology ... #Syndrome #TLS
Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of
Tumor lysis syndrome ... hyperphosphatemia, #hypocalcemia ... acutekidneyinjury #Pathophysiology ... #Presentation #TLS
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... An acute, life-threatening ... grade lymphoma & Acute ... Walid Malki, MD, MS ... #Syndrome #TLS
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... Cancer Related • Hypercalcemia ... malignancies Treatment ... Interleukin-2) • Tumor lysis ... cyclophosphamide) #Acute
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
thyroid, Sjogren syndrome ... “dropping head syndrome ... Generalized fatigue - ALS ... immunologic assay - MuSK ... aspiration and acute
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Blood transfusion, Hypercalcemia ... Etiology: • Pathophysiology ... Neurological symptoms: Acute ... , ADEM, Acute toxic ... epilepticus Treatment
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... hyperphosphatemia, hypercalcemia ... and progressive Acute ... anterior/posterior MSK ... : ACUTE, fever,
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
antibiotics TLS ... (tumor-lysis syndrome ... low Ca - q8 h TLS ... plasmapheresis Hypercalcemia ... → no immediate treatment