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treatment hematology sle disseminated druginduced erythematosus product reactions summary systemic activation causes cns coagulation comparison dic gonococcal gonorrhea gout hemophagocytic
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
thrombosis and/or blood-brain ... of Lupus Cerebritis ... CNS #neurology #rheumatology ... #cerebritis #diagnosis ... #management #treatment
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... and Management ... of SLE versus DIL ... Erythematosus #Diagnosis ... #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... Drug Induced Lupus ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Disseminated Gonococcal Infection - Diagnosis and Management Summary Bacteremic spread of the Gram-negative diplococci Neisseria gonorrhoeae. History
and Management ... : • 2 sets of blood ... with suspected DGl ... joints, knees, wrists ... #Management #Microbiology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... MAHA: TTP/HUS > DIC ... #Coagulation #diagnosis ... causes #treatment #management ... #hematology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... : -10% of all lupus ... #DIL #rheumatology ... #diagnosis #treatment ... #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... Auto-amplification loop Diagnosis ... Fibrinogen level, ↑ sIL ... #management #treatment ... #summary #rheumatology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... screen - determines blood ... pain, dark urine, DIC ... #Transfusions #diagnosis ... #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... the banked donor blood ... pain, dark urine, DIC ... #Transfusion #diagnosis ... #management #hematology
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