29 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... transformation to acute leukemia ... only curative treatment ... #Management #treatment ... #hematology #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic Leukemia ... • Most common leukemia ... minimal tumor burden Diagnosis ... #oncology #hematology ... #hemeonc #diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... -> AML: Blast crises ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
adults in the west ... with no early symptoms ... microglobulin Treatment ... #diagnosis #workup ... #oncology #hematology
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework

High Altitude Pulmonary Edema:
 • Accumulation
- Differential Diagnosis ... 10,000 ft) • Symptoms ... - Dyspnea at rest ... • Signs/Symptoms ... #differential #diagnosis
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
without other cause ... ARDS to explain symptoms ... : 33% • Treatment ... , and CXR with pulmonary ... #diagnosis #comparison
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... Imaging: CXR- pulmonary ... : >3 symptoms, or ... #oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... pattern of spread, B symptoms ... Treated Like Acute Leukemias ... Classification #pathophysiology ... #Hematology #Diagnosis
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Lysis Syndrome: • Pathophysiology ... Syndrome #TLS #diagnosis ... #management #hematology
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
inflammation Symptoms ... parenchyma Diagnosis ... function tests: ... mycobacteria Treatment ... #differential #diagnosis