37 results
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
symptomatology Differential ... ANCA-positive vasculitis ... ANCA-negative vasculitis ... , biopsy By Tess ... #differential #
Polyarteritis Nodosa (PAN) - Vasculitis Management Algorithm - ACR/VF 2021 Guidelines
 • Severe Disease → Remission
Nodosa (PAN) - Vasculitis ... Management Algorithm ... • Non-Severe Disease ... #Management #Treatment ... #rheumatology
Causes of Dyspnea - Differential Diagnosis Algorithm
Cardiac:
 • Dysrhythmia
 • Ischemia
 • Cardiomyopathy
 • Valvular disease
Causes of Dyspnea - Differential ... Diagnosis Algorithm ... Superior vena cava syndrome ... hypertension • Vasculitis ... #Diagnosis #Algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... • Cogan Syndrome ... Differential ... retinopathy Lab Tests ... #rheumatology #
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... Rebound effect from treatment ... , Vasculitides, ... IBD, Celiac disease ... Kawasaki, Nephrotic syndrome
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
, small-vessel vasculitis ... ) Differential Diagnosis ... Arthritis, AS Treatment ... #diagnosis #management ... signs #symptoms #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Initial screening test ... block • Sjogren syndrome ... Treatment: • ... Summary #diagnosis #rheumatology ... #management
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... fraction < 20% Differential ... hepatitis • Pulmonary ... #diagnosis #management ... #treatment #rheumatology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Autoimmune ANCA vasculitis ... anti-GBM) Other tests ... #differential # ... diagnosis #management ... #treatment
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
With associated pulmonary ... involvement: Anti-GBM Disease ... #differential # ... diagnosis #algorithm ... #rheumatology