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differential algorithm rheumatology causes testing classification erythematosus lactate lupus oncology acidosis agglutinin arthritis autoantibodies chronic cll cold criteria decrease dehydrogenase
Laboratory Testing in Hemolytic Anemia Intravascular vs Extravascular Hemolysis Reticulocytes Unconjugated bilirubin LDH Peripheral smear Haptoglobin Urine hemosiderin Urine hemoglobin Carboxyhemoglobin #Hemolytic #Anemia #Laboratory #Testing #workup
in Hemolytic Anemia ... Extravascular Hemolysis ... #Anemia #Laboratory ... #diagnosis #hematology ... #hemolysis
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... haptogbbulin #Hemolysis ... #Hemolytic #Anemia ... Differential #Causes #Workup ... #Hematology #Diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... ): SS, SC, SE, Sβ ... elliptocytosis, autoimmune hemolysis ... ARUPConsult @ARUPLabs #Hemolytic ... #workup #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
hemorrhage and hemolysis ... intravascular hemolysis ... out an immune hemolytic ... the severity of hemolysis ... #Workup #Hematology
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
• Asplenia Laboratory ... blood loss • Hemolytic ... anemia • Splenomegaly ... End-stage renal disease ... Increase #Decrease #Diagnosis
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... NEUROLOGIC - HEMOLYTIC ... the absence of hemolytic ... anemia #Diagnosis ... #Rheumatology #
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Defects: Sickle cell anemia ... Tests: - Haptoglobin ... Urobilinogen #Hemolysis ... #hematology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
bloodstream Hemolysis ... : • Hemolytic ... Microangiopathic hemolytic ... hemolysis • Ineffective ... myelofibrosis • Hemolysis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Diagnosis: • hemolytic ... • Compensated hemolysis ... intravascular hemolysis ... #hemolytic #anemia ... #hematology #diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... for workup, including ... blood loss, Acute hemolysis ... , deficiency anemia ... Vasculitides, IBD, Celiac disease
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