11 results
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Abnormal Coagulation Tests ... PT - Prolonged aPTT ... PT - Prolonged aPTT ... #Laboratory #Hematology ... #Diagnosis #Workup
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
Thromboplastin Time (PTT ... elevated in: • DIC ... • Underfilled test ... Thromboplastin #laboratory ... #hematology #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Hemorrhagic bullae ... INR < 2.3 - APTT ... #Coagulation #diagnosis ... causes #treatment #management ... #hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... of SLE versus DIL ... • Laboratory ... • Immunologic Workup ... #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
calcium-b) • Laboratory ... • Immunologic Workup ... • Laboratory ... • Immunologic Workup ... #diagnosis #management
Asboe-Hansen sign (also known as "indirect Nikolsky sign" or "Nikolsky II sign")

Asboe-Hansen sign is the extension
Best-detected by ... clinical tool for diagnosing ... evaluation of TEN ... #PhysicalExam #Video ... #Blister #Dermatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
- Differential Diagnosis ... cascade is intact - test ... inhibitor and lupus ... liver function tests ... #Hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
fulminans - DIC ... Autoimmune Vasculitis (lupus ... deficiency Work ... Fecal occult blood test ... Algorithm #Causes #dermatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... value is low, tests ... performed PT, PTT ... indirect antiglobulin tests ... #Workup #Hematology
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
calcium-b) • Laboratory ... • Immunologic Workup ... #DIL #rheumatology ... #diagnosis #treatment ... #management