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diagnosis dermatology management differential erythematosus systemic autoimmune classification dermatomyositis druginduced henoch hsp joint myositis oncology pain purpura schonlein symptoms table
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... gangrenosum • IBD ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... differential #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Sjögrens (15%) Skin ... , Vasculitis, Purpura ... erythematosus #signs ... symptoms #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... 3rd Decade Skin ... Clinical Features ... Erythematosus #Diagnosis #Rheumatology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... RNA Polymerase Ill ... • ANCA Vasculitis ... Autoantibodies #Rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Associated with skin ... Treatment: • Mild ... #Systemic #Lupus ... Summary #diagnosis #rheumatology
Staphylococcal Scalded Skin Syndrome (SSSS) A 5-year-old girl presents to the ED with a rash that started
Syndrome (SSSS) ... A 5-year-old ... the ED with a rash ... #Clinical #Photo ... Peds #Pediatrics #Dermatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
can present with rash ... anti-synthetase syndrome ... Classic triad of ILD ... Can also see mechanics ... Myositis #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... such as systemic lupus ... purpura: strong sign ... , and SLE) • Urinalysis ... differential #diagnosis #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... Prognosis: Usually mild ... 40, F:M 9:1 • Clinical ... #table #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... : • Clinical triad ... reticularis & skin ... (e.g. systemic lupus ... classification #rheumatology
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