22 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... gangrenosum • IBD ... Antiphospholipid-antibody syndrome ... differential #diagnosis #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Associated with skin ... block • Sjogren syndrome ... Treatment: • Mild ... diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Demyelinating syndromes ... #signs #symptoms
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Suspect: Clinical ... 3rd Decade Skin ... rashErythematous ... Non-autoimmune rheumatologic ... Clinical Features
Staphylococcal Scalded Skin Syndrome (SSSS)

A 5-year-old girl presents to the ED with a rash that started
Staphylococcal Scalded Skin ... Syndrome (SSSS) ... A 5-year-old ... the ED with a rash ... #Clinical #Photo
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
can present with rash ... anti-synthetase syndrome ... Classic triad of ILD ... Can also see mechanics ... Myositis #diagnosis #rheumatology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
(blue-purple) rash ... with edema • Erythematous ... rash on the face ... auricular papules Clinical ... Dermatomyositis #rheumatology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
Pathogenesis and Clinical ... systemic lupus erythematosus ... (SLE) Signs / ... Xeroderma (Dry skin ... Pathophysiology #Diagnosis #Signs
Lymphocutaneous Sporotrichiosis Infection

Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis?
Lymphocutaneous
painless nodular rash ... trauma leads to skin ... Papulonodular, erythematous ... painless, no systemic signs ... #photo #hand
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Fever is the main clinical ... Petechial or purpuric rash ... [SLE], AOSD) • ... #Rheumatology