31 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Rash • Human ... • Rheumatic fever ... lesions • Discoid lupus ... #joint #pain #skin ... #differential #diagnosis
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
SLE : systemic lupus ... ConnectiveTissueDiseases #ILD ... LungDisease #CTILD #Diagnosis ... #Differential #Comparison ... #Table #Pulmonary
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(SLE) General: Fever ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... lesions Abdominal pain ... (20%) Renal disease
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... 3rd Decade Skin ... Differential Diagnosis ... Arthritis: • Joint pain ... to: Arthritis, Fever
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
symptoms - Headache, fever ... Nausea, abdominal pain ... Cold #Urticaria #diagnosis ... #rheumatology # ... comparison #table
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... sudden onset of a rash ... - Rash: multiple ... Inflammation and pain ... ’s syndrome - Lupus
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
muscle weakness, rash ... Rheumatica • Pain ... proximal joints, Fever ... #differential #diagnosis ... #comparison #rheumatology
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... instability - New-onset fever ... sulfa-drug - Skin ... pain - Immunocompromised ... Dermatology #Rash
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Systemic lupus ... is the main clinical ... Petechial or purpuric rash ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Red Flags: • Fever ... lesions • Severe pain ... Autoimmune Vasculitis (lupus ... cryoglobulins • Skin