26 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Rash • Human ... • Rheumatic fever ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... differential #diagnosis
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... Inflammation and pain ... - Lupus - Leukemia ... : - Biopsy - Microscopic
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(SLE) General: Fever ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Demyelinating syndromes ... lesions Abdominal pain
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
triad (<10%): fever ... , rash, eosinophilia ... eosinophiluria, microscopic ... hematuria, mild ... Algorithm #nephrology #diagnosis
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Red Flags: • Fever ... lesions • Severe pain ... Autoimmune Vasculitis (lupus ... Sjogren's, GPA, EGPA, Microscopic ... cryoglobulins • Skin
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Diagnosis Framework ... • Bursitis • IBD ... thrombophlebitis Skin ... /swelling - Fever ... #differential #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... 3rd Decade Skin ... Differential Diagnosis ... Arthritis: • Joint pain ... to: Arthritis, Fever
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... instability - New-onset fever ... sulfa-drug - Skin ... pain - Immunocompromised ... #Diagnosis #
Inflammatory Joint Pain - Differential Diagnosis Algorithm 
Monoarticular
 • Gout (Podagra, Tophi)
 • Pseudogout
 • Early
Inflammatory Joint Pain ... - Differential Diagnosis ... Arthritis • Systemic Lupus ... Sicca) Syndrome ... polyangiitis (GPA)/microscopic
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Systemic lupus ... is the main clinical ... Petechial or purpuric rash ... SJIA], systemic lupus ... #Diagnosis #Management