29 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... gangrenosum • IBD ... Antiphospholipid-antibody syndrome ... differential #diagnosis #rheumatology
Acute Purpura Fulminans Skin Rash on Physical Exam 
60 year old male ITP s/p splenectomy 
1d
Skin Rash on Physical ... Exam 60 year old ... shock, multiorgan system ... #Fulminans #Skin ... #photo
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... Demyelinating syndromes ... symptoms #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... easy bruising to purpura ... (Petechial or purpuric ... rash) • Heart, ... #Rheumatology
Staphylococcal Scalded Skin Syndrome (SSSS)

A 5-year-old girl presents to the ED with a rash that started
Staphylococcal Scalded Skin ... Syndrome (SSSS) ... A 5-year-old ... the ED with a rash ... #Clinical #Photo
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Maculopapular rash ... Henoch-Schönlein purpura ... • Goodpasture syndrome ... #dermatology #rash ... #diagnosis #rheumatology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
weakness, less systemic ... can present with rash ... anti-synthetase syndrome ... Classic triad of ILD ... Myositis #diagnosis #rheumatology
DRESS Syndrome vs SJS/TEN
DRESS
 • Latency: 2-8 weeks
 • Rash: Morbilliform
 • Mucosal involvement: 50% have
DRESS Syndrome vs ... : 2-8 weeks • Rash ... involvement: 50% have mild ... : 4-28 days • Rash ... erythematous macules with purpuric
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Associated with skin ... block • Sjogren syndrome ... polymyositis overlap syndrome ... Treatment: • Mild ... Summary #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Mucocutaneous lymph node syndrome ... mucositis - Rash ... VASCULITIS: • Behçet Syndrome ... • Cogan Syndrome ... differential #diagnosis #rheumatology