16 results
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... weakness, less systemic ... can present with rash ... anti-synthetase syndrome ... Classic triad of ILD
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
- Differential Diagnosis ... arthritis - (Reiter’s syndrome ... arthritis - with the skin ... autoimmune disease ... like “butterfly rash
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... general feeling of ill ... Leukemia cutis Diagnosis ... #diagnosis #dermatology
Castleman's Disease and Associated Syndromes
HYALINE VASCULAR VARIANT
 • unicentric, HHV8-ve, children and young.
 • Hyalinized vessels
and Associated Syndromes ... fashion- onion skin ... Pathogenesis "IL6 ... Plasmablastic variant" Autoimmune ... Disease #Variants #Diagnosis
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Associated with skin ... block • Sjogren syndrome ... Treatment: • Mild ... #SLE #Summary #diagnosis ... #rheumatology #management
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Eosinophilia and Systemic ... rash in association ... withdrawal • Mild ... SinaiBmoreIMRes #DRESS #Syndrome ... #management
Penicillin Allergy Pathway for Antibiotic Prescription in Patients With Penicillin Allergy
Mild Reaction - Itching, Minor rash
mucosal involvement, skin ... Stevens-Johnson syndrome ... eosinophilia systemic ... symptoms syndrome ... Prescription #algorithm #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... Periodic fever syndromes ... Petechial or purpuric rash ... hypersensitivity syndromes ... #Diagnosis #Management
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
likely conditions (autoimmune ... IL-6, TNF-a, ? ... maculopapular rash ... episode (30%) Systemic ... #management #treatment
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Differential Diagnosis ... disease • Non-autoimmune ... deficiencies • Autoimmune ... Seizures • Strokes Skin