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algorithm management blood intravascular palpable petechiae petechial product reactions anemia arterial coagulation dic disseminated embolism extravascular hemolysis hemolytic hemolyticuremicsyndrome microangiopathy
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. TTP/HUS indicates thrombotic
Algorithm for workup ... of thrombocytopenia ... TTP/HUS indicates ... purpura/hemolytic ... , Hematology 2012
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH These rashes can be especially challenging and are associated with devastating differential
presents in thrombocytopenic ... rash, the diagnosis ... likely to have thrombocytopenia ... #Diagnosis #Dermatology ... #Purpuric #Rash
Thrombotic Microangiopathy - TTP VS HUS Big picture points : Often hard to differentiate the two entities,
Microangiopathy #thrombocytopenic ... #purpura #TTP # ... #thrombocytopenia ... #Comparison #Diagnosis ... #Table #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... inflammation • Thrombocytopenia ... : - Thrombocytopenia ... Diagnosis #hematology ... #dermatology
Causes of Purpura - Differential Diagnosis Non-PalpabIe → Palpable • Thrombocytopenia (HIT, ITP/HUS), Coagulation defects (DIC, warfarin
Causes of Purpura ... → Palpable • Thrombocytopenia ... (HIT, ITP/HUS), ... BrighamChiefs #Purpura ... #Causes #Differential
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Rash - Differential ... hemostasis: - Thrombocytopenia ... Henoch Schonlein Purpura ... : - Purpura fulminans ... #Causes #dermatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
transfusion • Thrombocytopenia ... Petechiae • Purpura ... Hemorrhagic bullae • Purpura ... MAHA + Thrombocytopenia ... #management #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
microangiopathy: Thrombotic thrombocytopenic ... purpura (TTP), ... uremic syndrome (HUS ... #differential # ... diagnosis #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
Evaluation for ... Thrombotic Thrombocytopenic ... Purpura Activity ... WBC count and differential ... #Workup #Hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Hyperviscosity, TTP ... Hyperhomocysteinemia - Heparin-induced ... thrombocytopenia ... of purpura fulminans ... pathophysiology #hematology
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