12 results
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Elevated Liver Function ... Tests (LFTs) - ... Chronic Viral Hepatitis ... injury) • Ischemic ... Diagnosis #hepatology #transaminitis
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... Injury Transaminase ... #Patterns #Liver ... #Injury #hepatology ... #LFTs #transaminitis
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... Liver Injury ... Injury? ... #Enzymes #LFTs ... #Cholestatic #Transaminitis
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... Injuryliver ... • Infections: Hepatitis ... hepatology #algorithm #Transaminitis ... #LFTs #hepatitis
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
Elevated Transaminases ... / Transaminitis ... Trauma: Shock liver ... • Autoimmune hepatitis ... #Elevated #Transaminases
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... Check Acute viral hepatitis ... specificity to elevated ... differential #Hepatology #transaminitis ... #LFTs #RValue #
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
(LFTs) Elevation ... Hepatocellular injury ... 2: Cholestatic injury ... #FunctionTest #LFTs ... #Elevation #Transaminitis
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Algorithm for Transaminitis ... Burak @kwburak #LFTs ... #Elevated #Abnormal ... #Transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Autoimmune: Autoimmune hepatitis ... specificity to elevated ... Chronic viral hepatitis ... #injury #hepatitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... • Alcoholic hepatitis ... • Others #LFTs