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Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Cholestatic Liver Injury ... Hepatocellular Liver Injury ... Hepatocellular injury ... = Cholestatic injury ... #Cholestatic #Transaminitis
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver Injury ... Patterns #Liver #Injury ... hepatology #LFTs #transaminitis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Drug-induced liver injury ... Diagnosis #hepatology #transaminitis
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Hepatocellular injury ... 2: Cholestatic injury ... LFTs #Elevation #Transaminitis
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Hepatocellular Liver Injury ... Framework: Liver Injury ... Hepatocellular Liver Injury ... Hepatocellular #Liver #Injury ... hepatology #algorithm #Transaminitis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
ALF): • Liver injury ... hepatocellular injury ... • Acute muscle injury ... Chronic muscle injury ... differential #Hepatology #transaminitis
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
Transaminases / Transaminitis ... images/10587 #Transaminitis
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
spinal artery injury ... function below injury ... below level of injury ... spinal artery injury ... below level of injury
Evaluation abnormal liver tests in pregnancy - Cholestatic Pattern - Hepatocellular Pattern #LFTs #transaminits #pregnancy #obgyn #obstetrics #hepatology #diagnosis
Pattern #LFTs #transaminits
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Algorithm for Transaminitis ... Elevated #Abnormal #Transaminitis
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