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hepatology algorithm injury hepatitis abnormal causes chemistry dili drug elevation enzymes function functiontest gastroenterology idiosyncratic induced interpretation liverenzymes liverfunctiontests management
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... Liver Injury Hepatocellular ... #Enzymes #LFTs ... #Cholestatic #Transaminitis ... #diagnosis #differential
Evaluation abnormal liver tests in pregnancy - Cholestatic Pattern - Hepatocellular Pattern #LFTs #transaminits #pregnancy #obgyn #obstetrics #hepatology #diagnosis
Evaluation abnormal liver ... in pregnancy - Cholestatic ... Pattern - Hepatocellular ... Pattern #LFTs ... #differential #
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
(LFTs) Elevation ... ALT ≥ 3x ULN Cholestatic ... #FunctionTest #LFTs ... #Elevation #Transaminitis ... #diagnosis #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Hepatocellular ... Burak @kwburak #LFTs ... #Elevated #Abnormal
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Hepatocellular Liver ... phosphatase) 2) Cholestatic ... Liver Injury Differential ... #Differential #Diagnosis ... #LFTs #hepatitis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... specificity to elevated ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... Tests (LFTs) - ... Differential Diagnosis ... #Differential # ... #transaminitis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... Calculate R-Value • Hepatocellular ... Mixed DILI • Cholestatic ... Idiosyncratic #differential
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... specificity to elevated ... injury #hepatitis #differential ... #diagnosis #algorithm
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... Diagnosis Algorithm ... • Others • Cholestatic ... • Others #LFTs
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